|
Herbal Medicines |
|
Bindarit
Capsaicin
Curcumin
Chongmyung-Tang
Epigallocatechin gallate
Cimicifuga rhizoma
Genistein
Ginkgo biloba
Hymenialdisine
Oren-gedoku-to
Polygala tenuifolia
Rosmarinus officinalis
Linn
Glucosidorum Tripterygii
tororum
Quercetin
Rehmannia glutinosa
Gallic acid esters (red
wine)
Sanguinarine
Sesquiterpene lactone
helenalin
Silymarin
Urtica dioica
Zingiberaceae
|
Zoja C, et al. Kidney Int
1998 ;53:726-34
Yu R, et al. Int J Vitam
Nutr Res 1998;68:114-9
Jobin C, et al.. J
Immunol 1999;163:3474-83
Kim HM, et al. J
Ethnopharmacol 1999;66:295-300
Yang F, et al. J Nutr
1998;128:2334-40
Hirabayashi T, et al..
Planta Med 1995;61:221-6
Tabary O, et al. Am J
Pathol 1999;155:473-81
Wei Z, et al.. Gen
Pharmacol 1999;33:369-75
Breton JJ, et al. J
Pharmacol Exp Ther 1997;282:459-66
Wang LM,et al.. J Pharm
Pharmacol 1997;49:102-4
Kim HM, et al.. J
Ethnopharmacol 1998;61:201-8
al-Sereiti MR, et al.
Indian J Exp Biol 1999;37:124-30
Wang ZG. Chung Kuo Chung
Hsi I Chieh Ho Tsa Chih 1997;17:348-50
Ishikawa Y, et al. J Am
Soc Nephrol 1999;10:2290-6
Kim HM,. et al. Pharmacol
Res 1999;40:171-6
Murase T, et al.
Arterioscler Thromb Vasc Biol 1999;19:1412-20
Chaturvedi MM, et al. J
Biol Chem 1997 28;272:30129-34
Lyss G, et al. J Biol
Chem 1998 11;273:33508-16
Saliou C, et al. FEBS
Lett 1998 27;440:8-12
Riehemann K, et al. FEBS
Lett 1999; 8;442:89-94
Surh Y. Mutat Res
1999;428:305-27 |
|
Therapeutic Approaches Aimed at Suppression of Cytokine/Chemokine Mediated
Stealth Virus Infection |
|
Therapeutic agent |
Reference to its effect on
cytokine/chemokine mediated activities |
|
Anti-oxidants |
|
Vitamin C
Vitamin E
N-acetyl-cysteine
Alpha-lipoic acid
Coenzyme Q10
Butylated hydroxytoluene
BHT |
Vlahopoulos S, et.al. Blood
1999;94:1878-89
Wu D, et.al.
Atherosclerosis. 1999; 7:297-307.
Gosset P, et.al. Eur
Respir J 1999;14:98-105
Suzuki YJ, et.al. Biochem
Biophys Res Commun 1992;189:1709-15
Hodges S, et.al.
Biofactors 1999;9:365-70
Hulten LM, et al.
Transplantation 1998;66(3):364-9 |
|
Diet and Nutritional
Supplements |
|
Asparagus cochinchinensis
Gamma linoleic acid
Omega-3 lipids
Fish oil
Flaxseed oil
Palm oil
Fiber
Butyrate
Yogurt
L-Glycine
L-Arginine
Zinc
Inosine
Taurine chloramine
S-adenosylmethionine
DHEA |
Kim H, et al. Int J
Immunopharmacol 1998;20(4-5):153-62
Dirks J, et.al.
Prostaglandins Leukot Essent Fatty Acids 1998;59:273-7
Venkatraman JT andChu WC
. J Am Coll Nutr 1999;18:602-13
James MJ, et al. Am J
Clin Nutr 2000;71(1 Suppl):343S-8S
James MJ, et al. Am J
Clin Nutr 2000;71(1 Suppl):343S-8S
Engelberts I, et.al. Br J
Nutr 1993;69:159-67
Andoh A, et.al. JPEN J
Parenter Enteral Nutr 1999;23(5 Suppl):S70-3
Andoh A et al. Clin Exp
Immunol 1999;118:23-9
Ha CL, et.al. J Food Prot
1999;62:181-8
Spittler A, et al. FASEB
J 1999 ;13:563-71
Haberstroh U, et al. J Am
Soc Nephrol 1998 ;9:203-10.
Connell P, et al. J Am
Coll Nutr 1997 ;16:411-7
Hasko G, et al. J Immunol
2000;164:1013-9
Kontny E, et al.
Arthritis Rheum 1999;42:2552-60
Watson WH, et al. Biochem
J 1999;342 ( Pt 1):21-5
Araghi-Niknam M, et al.
Proc Soc Exp Biol Med 1997 ;216:386-91 |
|
Anti-leukotriene medications |
|
Montelukast
Zileuton
|
Denizot Y, et al. Cytokine 1999;11:606-10
Aoki Y, et al. Am J
Physiol 1998;274:L1030-9 |
|
Over the Counter anti-ulcer
medications |
|
Sulglycotide
Rebamipide
Polaprezinc
|
Slomiany BL, Piotrowski J, Slomiany A.
Aihara M, et al.. Dig Dis
Sci 1998;43(9 Suppl):174S-180S
Shimada T, et al.. J
Pharmacol Exp Ther 1999;291:345-52 |
|
Over the Counter
anti-rheumatic medications |
|
Aspirin
Ibuprofen
Sodium salicylate
Nimesulide
Diclofenac
|
Shi X, et al. Mol Cell
Biochem 1999;199:93-102.
Stuhlmeier KM, et al.
Biochem Pharmacol 1999 1;57:313-20
Lemay S, et al. Clin
Diagn Lab Immunol 1999;6:567-72
Azab A, et al. J. Life
Sci 1998;63: 323-7
Henrotin YE, et al. Clin
Exp Rheumatol 1999;17:151-60 |
|
Prescription ani-rheumatic
drugs* |
|
Chloroquine
Sulfasalazine
D-penicillamine
Gold
Glucocorticoids
Methotrexate
Bucillamine
Quinine
Quinacrine
Thalidomide
|
Zhu X, et al.. Immunology
1993;80:122-6
Deleuran B, et al.
Cytokine 1992;4:403-9
Deleuran B, et al.
Cytokine 1992;4:403-9
Yoshida S, et al. Int
Immunol 1999;11:151-8
Bourke E, and Moynagh PN.
J Immunol 1999;163:2113-9.
Boiardi L, et al. Clin
Exp Rheumatol 1999;17:419-25
Matsuno H, et al.. Int J
Immunopharmacol 1998;20:295-304
Maruyama N, et al. Am J
Respir Cell Mol Biol 1994;10:514-20
Bondeson J, and Sundler
R. Gen Pharmacol 1998;30:357-66
Dunzendorfer S, et al.
Immunopharmacology 1999;43:59-64 |
|
Antibiotics that suppress
chemokines* |
|
Clarithromycin
Roxithromycin
Erythromycin
Doxycycline
Minocycline
|
Matsuoka N, et al. Clin Exp Immunol 1996;104:501-8
Nonaka M, et al. Acta
Otolaryngol Suppl 1998;539:71-5
Takizawa H, et al. J. Am
J Respir Crit Care Med 1997;156:266-71
Attur MG, et al. J
Immunol 1999 15;162:3160-7
Attur MG, et al. J
Immunol 1999 15;162:3160-7 |
|
Other Drugs that can
suppress chemokines* |
|
ACE Inhibitors+
HMG-CoA reductase#
inhibitors
Nitric oxide synthase
inhibitors
Ca(2+)-channel blockers
PGE(2) including agents
Nucloside analogue
Desferrioxamine
Pentoxifylline
Furosemide
Thyroxine
Vitamin B3
Vitamin B6
Vitamin B12
Vitamin D
Progesterone
Estrogens
Bile acids
Ketamine
Morphine
Levodopa
Selegiline
Sertraline
Trazadone
Haloperidol
|
Gullestad L, et al. J Am Coll Cardiol 1999;34:2061-7
Ortego M, et al. J.
Atherosclerosis 1999;147:253-61
Lane TE,et al. J
Neurovirol 1999;5:48-54
Rodler S, et al. J Mol
Cell Cardiol 1995;27:2295-302
Kunkel SL, et al. J Biol
Chem 1988 15;263:5380-4
Zidek Z, et al. Eur J
Pharmacol 1999 2;376:91-100
Martelius T, et al.
Transplantation 1999 15;68:1753-61
Neuner P, et al.
Immunology 1994 ;83:262-7
Yuengsrigul A, et al. Ann
Allergy Asthma Immunol 1999;83:559-66
Rittenhouse PA, and Redei
E. Endocrinology 1997 ;138:1434-9
Pero RW, et al. Mol Cell
Biochem 1999;193:119-25
Roubenoff R,et al.
Arthritis Rheum 1995;38:105-9
Buccellato FR, et al. .
FASEB J 1999;13:297-304
Harant H, et al.. Eur J
Biochem 1997 15;250:63-71
Vassiliadou N, et al. J
Immunol 1999;15;162:7510-8
Inadera H, et al.
Endocrinology 2000;141:50-9
Saitoh O, et al. J
Gastroenterol Hepatol 1998;13:1212-7
Kawasaki T, et al. Anesth
Analg 1999;89:665-9
Grimm MC, et al. Ann N Y
Acad Sci 1998 1;840:9-20
Bessler H, et al. Biomed
Pharmacother 1999;53:141-5
Muller T, J Neural Transm
Suppl 1998;52:321-8.
Maes M, et al.
Neuropsychopharmacology 1999;20:370-9
Maes M, et al.
Neuropsychopharmacology 1999;20:370-9
Moots RJ, et al. Ann
Rheumatic Dis 1999;58:585-7 |
|
Chemokine and chemokine
receptor blocking agents |
|
Heparin*
Chondroitin
Mannans
Peptide T
|
Ramdin L, et al. Clin Exp
Allergy 1998;28:616-24
Kuschert GS et al.
Biochemistry 1999;38:12959-68
Mbemba E, et al. Virology
1999;265:354-64
Redwine LS, et al. Clin
Immunol 1999;93:124-31 |
|
Legend to the Table |
|
* The use of these
medications solely for stealth virus infections is not being suggested.
This does not, however, preclude an assessment of their potential
anti-stealth virus activity in patients in whom the use of the
medication is medically indicated.
+
ACE Angiotension converting enzyme
#
Cholesterol lowering |
|